Transformative Nanomedicine of an Amphiphilic Camptothecin Prodrug for Long Circulation and High Tumor Uptake in Cancer Therapy

Author:

Zhang Fuwu1,Zhu Guizhi1,Jacobson Orit1,Liu Yi12,Chen Kai3,Yu Guocan1,Ni Qianqian1,Fan Jing1,Yang Zhen1ORCID,Xu Frederick1,Fu Xiao1,Wang Zhe1,Ma Ying1,Niu Gang1,Zhao Xiaobin4,Chen Xiaoyuan1ORCID

Affiliation:

1. Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, Maryland 20892, United States

2. School of Engineering, China Pharmaceutical University, Nanjing 210009, P. R. China

3. Molecular Imaging Center, Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, United States

4. The White Oak Group, Washington, D.C. 20006, United States

Funder

Natural Science Foundation of Jiangsu Province

National Institute of Biomedical Imaging and Bioengineering

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

General Physics and Astronomy,General Engineering,General Materials Science

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