Development of Optimized Tissue-Factor-Targeted Peptide Amphiphile Nanofibers to Slow Noncompressible Torso Hemorrhage

Author:

Klein Mia K.1,Kassam Hussein Aziz1,Lee Robert H.23ORCID,Bergmeier Wolfgang23,Peters Erica B.1ORCID,Gillis David C.1ORCID,Dandurand Brooke R.1,Rouan Jessica R.1,Karver Mark R.4,Struble Mark D.4,Clemons Tristan D.456ORCID,Palmer Liam C.45ORCID,Gavitt Brian7,Pritts Timothy A.8,Tsihlis Nick D.1ORCID,Stupp Samuel I.4591011ORCID,Kibbe Melina R.112ORCID

Affiliation:

1. Department of Surgery and Center for Nanotechnology in Drug Delivery, University of North Carolina, Chapel Hill, North Carolina 27599, United States

2. Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina 27599, United States

3. UNC Blood Research Center, University of North Carolina, Chapel Hill, North Carolina 27514, United States

4. Simpson Querrey Institute, Northwestern University, Chicago, Illinois 60611, United States

5. Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States

6. School of Molecular Sciences, University of Western Australia, Perth, WA 6009, Australia

7. United States Air Force School of Aerospace Medicine, Wright-Patterson AFB, Ohio 45433, United States

8. Department of Surgery, University of Cincinnati, Cincinnati, Ohio 45267, United States

9. Department of Materials Science and Engineering, Northwestern University,, Evanston, Illinois 60208, United States

10. Department of Medicine, Northwestern University, Chicago, Illinois 60611, United States

11. Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208, United States

12. Department of Biomedical Engineering, University of North Carolina, Chapel Hill, North Carolina 27599, United States

Funder

School of Medicine, University of North Carolina at Chapel Hill

National Heart, Lung, and Blood Institute

American Heart Association

U.S. Department of Defense

American Australian Association

Division of Materials Research

International Institute for Nanotechnology, Northwestern University

Center for Regenerative Nanomedicine, Northwestern University

State of Illinois

Publisher

American Chemical Society (ACS)

Subject

General Physics and Astronomy,General Engineering,General Materials Science

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