Adipocyte-Targeting Type I AIE Photosensitizer for Obesity Treatment via Photodynamic Lipid Peroxidation

Author:

Lee Michelle M. S.1,Lin Dan Min2,Chau Joe H. C.1,Yu Eric Y.1,Ding Dan3ORCID,Kwok Ryan T. K.1ORCID,Wang Dong2ORCID,Tang Ben Zhong14ORCID

Affiliation:

1. Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong 999077, China

2. Centre for AIE Research, Shenzhen Key Laboratory of Polymer Science and Technology, Guangdong Research Center for Interfacial Engineering of Functional Materials, College of Material Science and Engineering, Shenzhen University, Shenzhen 518061, China

3. State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education, and College of Life Sciences, Nankai University, Tianjin 300071, China

4. School of Science and Engineering, Shenzhen Institute of Aggregate Science and Technology, The Chinese University of Hong Kong, Shenzhen, Guangdong 518172, China

Funder

Research Grants Council, University Grants Committee

National Key Research and Development Program of China

Science and Technology Foundation of Shenzhen City

Natural Science Foundation of Guangdong Province for Distinguished Young Scholars

Innovation and Technology Commission

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

General Physics and Astronomy,General Engineering,General Materials Science

Reference44 articles.

1. Obesity and Overweight. World Health Organization, June 9, 2021. https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight (accessed 16 September 2022).

2. Causes and control of excess body fat

3. Mechanisms linking obesity to insulin resistance and type 2 diabetes

4. Mechanisms linking obesity with cardiovascular disease

5. Myocardial infarction and coronary pathology in severely obese people examined at autopsy

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