Engineered Toll-like Receptor Nanoagonist Binding to Extracellular Matrix Elicits Safe and Robust Antitumor Immunity

Author:

Yang Liu1,Lang Yue2,Wu Haoguang1,Xiang Kaiyan1,Wang Yuanzheng1,Yu Mengqi34,Liu Yu1,Yang Bowei34,He Liangcan5ORCID,Lu Guangming1ORCID,Ni Qianqian146,Chen Xiaoyuan3467ORCID,Zhang Longjiang1

Affiliation:

1. Department of Radiology, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002 Jiangsu, China

2. National Clinical Research Center of Kidney Diseases, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002 Jiangsu, China

3. Department of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore

4. Nanomedicine Translational Research Program, NUS Center for Nanomedicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore

5. School of Medicine and Health, Harbin Institute of Technology, Harbin 150080, China

6. Clinical Imaging Research Centre, Centre for Translational Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore

7. Institute of Molecular and Cell Biology, Agency for Science, Technology, and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore 138673, Singapore

Funder

Ministry of Science and Technology of the People's Republic of China

National Medical Research Council

Natural Science Foundation of Jiangsu Province

National University of Singapore

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

General Physics and Astronomy,General Engineering,General Materials Science

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