Transgenerational Inheritance Effects of Copper Oxide Nanoparticles (CuONPs) Induced Asthenospermia and Infertility via Gamete H3K9me3 Insufficiency Pathway in Mice

Author:

Shaoyong Weike12,Wang Wusu3,Pan Bo4,Liu Rui3,Yin Lin3,Wangjie Reshouyang5,Tian Haolun6,Wang Yizhen1,Jin Mingliang1ORCID

Affiliation:

1. Key Laboratory of Molecular Animal Nutrition, Ministry of Education; Key Laboratory of Animal Feed and Nutrition of Zhejiang Province; College of Animal Sciences, Zhejiang University, Hangzhou 310058, China

2. Center for Metabolic & Gastroenterology, Institute of Translational Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China

3. International Institutes of Medicine, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu 322000, China

4. Key Laboratory of Adaptation and Evolution of Plateau Biota, Northwest Institute of Plateau Biology, University of Chinese Academy of Sciences, Beijing 100049, China

5. Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China

6. College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi 712100, China

Funder

Key Research and Development Program of Zhejiang Province

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

American Chemical Society (ACS)

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