Core–Satellite Nanomedicines for in Vivo Real-Time Monitoring of Enzyme-Activatable Drug Release by Fluorescence and Photoacoustic Dual-Modal Imaging

Author:

Li Xianlei12,Bottini Massimo13,Zhang Luyao24,Zhang Shuai5,Chen Jing1,Zhang Tingbin1,Liu Lu12,Rosato Nicola3,Ma Xibo25,Shi Xinghua26,Wu Yan12ORCID,Guo Weisheng7ORCID,Liang Xing-Jie12ORCID

Affiliation:

1. CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, No. 11, First North Road, Zhongguancun, Beijing 100190, P. R. China

2. University of Chinese Academy of Sciences, Beijing 100049, P. R. China

3. Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy

4. LNM, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190, P. R. China

5. CAS Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, P. R. China

6. CAS Key Laboratory for Nanosystem and Hierarchy Fabrication, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing 100190, P. R. China

7. Translational Medicine Center, State Key Laboratory of Respiratory Disease, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou 510260, P. R. China

Funder

Ministry of Science and Technology of the People's Republic of China

Deutsche Forschungsgemeinschaft

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

American Chemical Society (ACS)

Subject

General Physics and Astronomy,General Engineering,General Materials Science

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