Targeted Brain Delivery of Rabies Virus Glycoprotein 29-Modified Deferoxamine-Loaded Nanoparticles Reverses Functional Deficits in Parkinsonian Mice

Author:

You Linhao12,Wang Jing23,Liu Tianqing4,Zhang Yinlong25,Han Xuexiang23ORCID,Wang Ting6,Guo Shanshan23,Dong Tianyu1,Xu Junchao23,Anderson Gregory J.4,Liu Qiang7,Chang Yan-Zhong1,Lou Xin6,Nie Guangjun23ORCID

Affiliation:

1. Laboratory of Molecular Iron Metabolism, College of Life Science, Hebei Normal University, Shijiazhuang, Hebei Province 050024, China

2. CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing 100190, China

3. University of Chinese Academy of Sciences, Beijing 100049, China

4. QIMR Berghofer Medical Research Institute, PO Royal Brisbane Hospital, Brisbane, QLD 4029, Australia

5. College of Pharmaceutical Science, Jilin University, Changchun 130021, China

6. Department of Radiology, The People’s Liberation Army General Hospital, No. 28 Fuxing Road, Beijing 100853, China

7. Chinese Academy of Sciences Key Laboratory of Brain Function and Disease, and School of Life Sciences, University of Science and Technology of China, Hefei 230026, China

Funder

Queensland Government

National Natural Science Foundation of China

Chinese Academy of Sciences

Beijing Municipal Science and Technology Commission

Publisher

American Chemical Society (ACS)

Subject

General Physics and Astronomy,General Engineering,General Materials Science

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