Enhancing Specific Fluorescence In Situ Hybridization with Quantum Dots for Single-Molecule RNA Imaging in Formalin-Fixed Paraffin-Embedded Tumor Tissues

Author:

Zhao Zeyin12,Jiang Mengyuan23,He Chen2,Yin Wenjuan2,Feng Yawei12,Wang Peng45,Ying Lisha2,Fu Ting12,Su Dan2,Peng Ruizi12ORCID,Tan Weihong12ORCID

Affiliation:

1. Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha, Hunan 410082, China

2. Department of Pathology, Zhejiang Cancer Hospital, Key Laboratory of Zhejiang Province for Aptamers and Theranostics, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China

3. School of Chemistry and Materials Science, University of Science and Technology of China, Hefei, Anhui 230026, China

4. School of Molecular Medicine, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, Zhejiang 310024, China

5. Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China

Funder

Natural Science Foundation of Hunan Province

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Zhejiang Leading Innovation and Entrepreneurship Team

Zhejiang Kunpeng Program

Publisher

American Chemical Society (ACS)

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