Intrinsic Antibacterial Activity of Nanoparticles Made of β-Cyclodextrins Potentiates Their Effect as Drug Nanocarriers against Tuberculosis

Author:

Machelart Arnaud1,Salzano Giuseppina2,Li Xue2,Demars Aurore3,Debrie Anne-Sophie1,Menendez-Miranda Mario2,Pancani Elisabetta2,Jouny Samuel1,Hoffmann Eik1,Deboosere Nathalie1,Belhaouane Imène1,Rouanet Carine1,Simar Sophie4,Talahari Smaïl4,Giannini Valerie5,Villemagne Baptiste6,Flipo Marion6,Brosch Roland5,Nesslany Fabrice4,Deprez Benoit6,Muraille Eric37,Locht Camille1,Baulard Alain R.1,Willand Nicolas6,Majlessi Laleh5,Gref Ruxandra2ORCID,Brodin Priscille1ORCID

Affiliation:

1. Université de Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 8204 - CIIL - Center for Infection and Immunity of Lille, F-59000 Lille, France

2. Université Paris Sud, Université Paris-Saclay, CNRS, UMR 8214 - Institute for Molecular Sciences of Orsay (ISMO), F-91405 Orsay, France

3. Research Unit in Microorganisms Biology (URBM), Laboratory of Immunology and Microbiology, Université de Namur, Narilis, B-5000 Namur, Belgium

4. Université de Lille, Institut Pasteur de Lille, EA 4483, F-59000 Lille, France

5. Institut Pasteur, Unit for Integrated Mycobacterial Pathogenomics, Paris, CNRS UMR 3525, 25 Rue du Dr. Roux, F-75015 Paris, France

6. Université de Lille, INSERM, Institut Pasteur de Lille, U1177 - Drugs and Molecules for living Systems, F-59000 Lille, France

7. Laboratory of Parasitology, Faculty of Medicine, Université Libre de Bruxelles, B-1070 Brussels, Belgium

Funder

FP7 Health

Agence Nationale de la Recherche

FP7 People: Marie-Curie Actions

European Regional Development Fund

Fondation pour la Recherche M?dicale

Institut Pasteur

FP7 Ideas: European Research Council

European Molecular Biology Organization

R?gion Hauts-de-France

Publisher

American Chemical Society (ACS)

Subject

General Physics and Astronomy,General Engineering,General Materials Science

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