α-Synuclein Oligomers Displace Monomeric α-Synuclein from Lipid Membranes-Reference-Cited by-同舟云学术

α-Synuclein Oligomers Displace Monomeric α-Synuclein from Lipid Membranes

Published:2024-06-25 Issue:27 Volume:18 Page:17469-17482
ISSN:1936-0851
Container-title:ACS Nano
language:en
Short-container-title:ACS Nano

Author:

Šneiderienė Greta¹,Czekalska Magdalena A.¹²³,Xu Catherine K.¹^ORCID,Jayaram Akhila K.¹⁴,Krainer Georg¹⁵^ORCID,Arter William E.¹,Peter Quentin A. E.¹,Castellana-Cruz Marta¹,Saar Kadi Liis¹^ORCID,Levin Aviad¹^ORCID,Mueller Thomas²,Fiedler Sebastian²,Devenish Sean R. A.²,Fiegler Heike²,Kumita Janet R.¹⁶^ORCID,Knowles Tuomas P. J.¹⁴

Affiliation:

1. Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom

2. Fluidic Analytics Limited, Unit A, The Paddocks Business Centre, Cherry Hinton Road, Cambridge CB1 8DH, United Kingdom

3. Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Street, 02-093 Warsaw, Poland

4. Cavendish Laboratory, University of Cambridge, J J Thomson Avenue, Cambridge CB3 0HE, United Kingdom

5. Institute of Molecular Biosciences (IMB), University of Graz, Humboldtstraße 50, 8010 Graz, Austria

6. Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, United Kingdom

Funder

Engineering and Physical Sciences Research Council

Medical Research Council

European Research Council

St. John's College, University of Oxford

H2020 Marie Sklodowska-Curie Actions

Wolfson College, University of Oxford

University of Oxford

University of Cambridge

Frances and Augustus Newman Foundation

Cambridge Trust

Fluidic Analytics Ltd.

Rhodes Trust

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsnano.3c10889

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4. Defining α-synuclein species responsible for Parkinson’s disease phenotypes in mice

5. Brain infusion of α-synuclein oligomers induces motor and non-motor Parkinson’s disease-like symptoms in mice