Enhancing Catalytic Activity of a Nickel Single Atom Enzyme by Polynary Heteroatom Doping for Ferroptosis-Based Tumor Therapy

Author:

Zhu Yang12,Wang Wenyu3,Gong Peng1,Zhao Yafei3ORCID,Pan Yuanbo2,Zou Jianhua2,Ao Rujiang1,Wang Jun1,Cai Huilan1,Huang Hongwei1,Yu Meili1,Wang Huijuan4,Lin Lisen1,Chen Xiaoyuan2ORCID,Wu Yuen35ORCID

Affiliation:

1. MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou 350108, China

2. Departments of Diagnostic Radiology, Surgery, Chemical and Biomolecular Engineering, and Biomedical Engineering, Yong Loo Lin School of Medicine and Faculty of Engineering, National University of Singapore, Singapore 117597, Singapore

3. First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230026, China

4. Experimental Center of Engineering and Material Science, University of Science and Technology of China, Hefei 230026, China

5. Dalian National Laboratory for Clean Energy, Dalian 116023, China

Funder

Ministry of Science and Technology of the People's Republic of China

National Medical Research Council

China Postdoctoral Science Foundation

Central University Basic Research Fund of China

National Research Foundation Singapore

National University of Singapore

Natural Science Foundation of Hefei

Publisher

American Chemical Society (ACS)

Subject

General Physics and Astronomy,General Engineering,General Materials Science

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