Conformal Nanoencapsulation of Allogeneic T Cells Mitigates Graft-versus-Host Disease and Retains Graft-versus-Leukemia Activity-Reference-Cited by-同舟云学术

Conformal Nanoencapsulation of Allogeneic T Cells Mitigates Graft-versus-Host Disease and Retains Graft-versus-Leukemia Activity

Published:2016-05-31 Issue:6 Volume:10 Page:6189-6200
ISSN:1936-0851
Container-title:ACS Nano
language:en
Short-container-title:ACS Nano

Author:

Zhao Shuting,Zhang Lingling¹,Han Jianfeng,Chu Jianhong²,Wang Hai,Chen Xilin,Wang Youwei,Tun Norm,Lu Lanchun,Bai Xue-Feng,Yearsley Martha,Devine Steven,He Xiaoming,Yu Jianhua

Affiliation:

1. Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032, China

2. Suzhou Institute of Blood and Marrow Transplantation, Soochow University, Suzhou 215000, China

Funder

National Cancer Institute

National Institute of Allergy and Infectious Diseases

American Cancer Society

Publisher

American Chemical Society (ACS)

Subject

General Physics and Astronomy,General Engineering,General Materials Science

Link

https://pubs.acs.org/doi/pdf/10.1021/acsnano.6b02206

Reference46 articles.

1. IL-22 deficiency in donor T cells attenuates murine acute graft-versus-host disease mortality while sparing the graft-versus-leukemia effect

2. Blockade of interleukin-23 signaling results in targeted protection of the colon and allows for separation of graft-versus-host and graft-versus-leukemia responses

3. A diagnostic window for the treatment of acute graft-versus-host disease prior to visible clinical symptoms in a murine model

4. Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans

5. Innate protection from graft-versus-host disease

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