Synthesis, Molecular Modeling, and Biological Studies of Novel Piperidine-Based Analogues of Cocaine:  Evidence of Unfavorable Interactions Proximal to the 3α-Position of the Piperidine Ring

Author:

Petukhov Pavel A.1,Zhang Jianrong1,Wang Cheng Z.1,Ye Yan Ping1,Johnson Kenneth M.1,Kozikowski Alan P.1

Affiliation:

1. Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy (MC 781), University of Illinois at Chicago, 833 S. Wood Street 539, Chicago, Illinois 60612, Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas 77555-1031, and Georgetown University Medical Center, 3900 Reservoir Road, N.W., Washington, DC 20007

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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