Reaction Mechanism of the Mandelate Anion Racemization Catalyzed by Mandelate Racemase Enzyme: A QM/MM Molecular Dynamics Free Energy Study-Reference-Cited by-同舟云学术

Reaction Mechanism of the Mandelate Anion Racemization Catalyzed by Mandelate Racemase Enzyme: A QM/MM Molecular Dynamics Free Energy Study

Published:2005-10-15 Issue:44 Volume:109 Page:21089-21101
ISSN:1520-6106
Container-title:The Journal of Physical Chemistry B
language:en
Short-container-title:J. Phys. Chem. B

Author:

Prat-Resina Xavier¹,González-Lafont Àngels¹,Lluch José M.¹

Affiliation:

1. Departament de Química, Universitat Autònoma de Barcelona, 08193 Bellaterra (Barcelona), Spain, and Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, 08193 Bellaterra (Barcelona), Spain

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jp052239d

Reference62 articles.

1. Mandelate Racemase: Structure-Function Studies of a Pseudosymmetric Enzyme

2. Electrophilic catalysis can explain the unexpected acidity of carbon acids in enzyme-catalyzed reactions

3. Mechanism of the Reaction Catalyzed by Mandelate Racemase: Importance of Electrophilic Catalysis by Glutamic Acid 317

4. Mandelate Racemase in Pieces: Effective Concentrations of Enzyme Functional Groups in the Transition State

5. Hydrophobic Nature of the Active Site of Mandelate Racemase

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Uncovering a superfamily of nickel-dependent hydroxyacid racemases and epimerases;Scientific Reports;2020-10-22

2. Carbon Acidity in Enzyme Active Sites;Frontiers in Bioengineering and Biotechnology;2019-02-19

3. Molecular dynamics perspective on the thermal stability of mandelate racemase;Journal of Biomolecular Structure and Dynamics;2018-01-25

4. A Paradigm for C H Bond Cleavage: Structural and Functional Aspects of Transition State Stabilization by Mandelate Racemase;Structural and Mechanistic Enzymology;2017

5. Directed evolution of mandelate racemase by a novel high-throughput screening method;Applied Microbiology and Biotechnology;2016-08-24