An Experimental Approach To Evaluate the Impact of Impaired Transport Function on Hepatobiliary Drug Disposition Using Mrp2-Deficient TR– Rat Sandwich-Cultured Hepatocytes in Combination with Bcrp Knockdown-Reference-Cited by-同舟云学术

An Experimental Approach To Evaluate the Impact of Impaired Transport Function on Hepatobiliary Drug Disposition Using Mrp2-Deficient TR– Rat Sandwich-Cultured Hepatocytes in Combination with Bcrp Knockdown

Published:2014-01-30 Issue:3 Volume:11 Page:766-775
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Yang Kyunghee¹,Pfeifer Nathan D.¹,Hardwick Rhiannon N.¹,Yue Wei¹,Stewart Paul W.¹,Brouwer Kim L. R.¹

Affiliation:

1. Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, §Curriculum in Toxicology, and ⊥Department of Biostatistics, UNC Gillings School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, 27599-7569, United States

Funder

National Institutes of Health

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp400471e

Reference43 articles.

1. Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance

2. A multidrug resistance transporter from human MCF-7 breast cancer cells

3. Breast Cancer Resistance Protein Directly Confers SN-38 Resistance of Lung Cancer Cells

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