Synthesis of (S)-3-(N-Methylamino)-1-(2-thienyl)propan-1-ol: Revisiting Eli Lilly's Resolution−Racemization−Recycle Synthesis of Duloxetine for Its Robust Processes
Author:
Affiliation:
1. Research & Development Center, Nagase & Co., Ltd. 2-2-3 Murotani, Nishi-ku, Kobe, 651-2241 Japan
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op060118l
Reference16 articles.
1. Identification and Comparison of Impurities in Fluoxetine Hydrochloride Synthesized by Seven Different Routes
2. A practical asymmetric synthesis of (R)-fluoxetine and its major metabolite (R)-norfluoxetine
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