1. Department of Chemistry and Department of Physiology and Functional Genomics, Shands Cancer Center and University of Florida Genetics Institute, Center for Research at the Bio/Nano Interface, McKnight Brain Institute, University of Florida, Gainesville, Florida 32611-7200, and Biomedical Engineering Center, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, China