Synthesis and Evaluation of New Hsp90 Inhibitors Based on a 1,4,5-Trisubstituted 1,2,3-Triazole Scaffold-Reference-Cited by-同舟云学术

Synthesis and Evaluation of New Hsp90 Inhibitors Based on a 1,4,5-Trisubstituted 1,2,3-Triazole Scaffold

Published:2014-03-17 Issue:6 Volume:57 Page:2258-2274
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Taddei Maurizio¹,Ferrini Serena¹,Giannotti Luca¹,Corsi Massimo¹,Manetti Fabrizio¹,Giannini Giuseppe²,Vesci Loredana²,Milazzo Ferdinando M.²,Alloatti Domenico²,Guglielmi Mario B.²,Castorina Massimo²,Cervoni Maria L.²,Barbarino Marcella²,Foderà Rosanna²,Carollo Valeria²,Pisano Claudio²,Armaroli Silvia³,Cabri Walter²

Affiliation:

1. Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena, Via A. Moro 2, I-53100 Siena, Italy

2. R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A., Via Pontina Km 30,400, I-00040, Pomezia, Roma, Italy

3. Sigma-Tau Research Switzerland S.A., Via Motta, 2a, CH-6850 Mendrisio-Stazione, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm401536b

Reference34 articles.

1. Heat shock proteins in the regulation of apoptosis: new strategies in tumor therapy