Understanding the Impact of the P-loop Conformation on Kinase Selectivity-Reference-Cited by-同舟云学术

Understanding the Impact of the P-loop Conformation on Kinase Selectivity

Published:2011-05-24 Issue:6 Volume:51 Page:1199-1204
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Guimarães Cristiano R. W.¹,Rai Brajesh K.¹,Munchhof Michael J.¹,Liu Shenping¹,Wang Jian¹,Bhattacharya Samit K.¹,Buckbinder Leonard¹

Affiliation:

1. Worldwide Medicinal Chemistry Department, ‡Computational Sciences Center of Emphasis, §Department of Structural Biology and Biophysics, and ∥CVMED - Target Exploration, Pfizer Global Research and Development, Eastern Point Road, Groton, Connecticut 06340, United States

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ci200153c

Reference19 articles.

1. Predicting Kinase Selectivity Profiles Using Free-Wilson QSAR Analysis

2. High-Throughput Structural Biology in Drug Discovery: Protein Kinases

3. The design, synthesis, and evaluation of 8 hybrid DFG-out allosteric kinase inhibitors: A structural analysis of the binding interactions of Gleevec®, Nexavar®, and BIRB-796

4. Protein Kinase Inhibitors: Insights into Drug Design from Structure

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