HCV NS5A Replication Complex Inhibitors. Part 4.1 Optimization for Genotype 1a Replicon Inhibitory Activity-Reference-Cited by-同舟云学术

HCV NS5A Replication Complex Inhibitors. Part 4.1 Optimization for Genotype 1a Replicon Inhibitory Activity

Published:2013-04-10 Issue:5 Volume:57 Page:1976-1994
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

St. Laurent Denis R.¹,Serrano-Wu Michael H.¹,Belema Makonen¹,Ding Min¹,Fang Hua¹,Gao Min¹,Goodrich Jason T.¹,Krause Rudolph G.¹,Lemm Julie A.¹,Liu Mengping¹,Lopez Omar D.¹,Nguyen Van N.¹,Nower Peter T.¹,O’Boyle Donald R.¹,Pearce Bradley C.¹,Romine Jeffrey L.¹,Valera Lourdes¹,Sun Jin-Hua¹,Wang Ying-Kai¹,Yang Fukang¹,Yang Xuejie¹,Meanwell Nicholas A.¹,Snyder Lawrence B.¹

Affiliation:

1. Departments of †Medicinal Chemistry, ‡Virology, and §Computer-Aided Drug Design, Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, Connecticut 06492, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm301796k

Reference75 articles.

1. HCV NS5A replication complex inhibitors. Part 3: discovery of potent analogs with distinct core topologies

2. Evolving epidemiology of hepatitis C virus

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