Synchrotron Radiation Provides a Plausible Explanation for the Generation of a Free Radical Adduct of Thioxolone in Mutant Carbonic Anhydrase II-Reference-Cited by-同舟云学术

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Synchrotron Radiation Provides a Plausible Explanation for the Generation of a Free Radical Adduct of Thioxolone in Mutant Carbonic Anhydrase II

Published:2010-09-16 Issue:19 Volume:1 Page:2898-2902
ISSN:1948-7185
Container-title:The Journal of Physical Chemistry Letters
language:en
Short-container-title:J. Phys. Chem. Lett.

Author:

Sippel Katherine H.¹,Genis Caroli¹,Govindasamy Lakshmanan¹,Agbandje-McKenna Mavis¹,Kiddle James J.²,Tripp Brian C.²³,McKenna Robert¹

Affiliation:

1. Department of Biochemistry and Molecular Biology, P.O. Box 100245, College of Medicine, University of Florida, Gainesville, Florida 32610

2. Department of Chemistry, Western Michigan University, Kalamazoo, Michigan 49008

3. Department of Biological Sciences, Western Michigan University, Kalamazoo, Michigan 49008

Publisher

American Chemical Society (ACS)

Subject

General Materials Science,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jz100954h

Reference33 articles.

1. Carbonic Anhydrase as a Model for Biophysical and Physical-Organic Studies of Proteins and Protein−Ligand Binding

2. Carbonic Anhydrase

3. Inhibition and Modification of Human Carbonic Anhydrase B with Bromoacetate and Iodoacetamide

4. Inhibition Profiling of Human Carbonic Anhydrase II by High-Throughput Screening of Structurally Diverse, Biologically Active Compounds

5. Carbonic anhydrase inhibitors: Thioxolone versus sulfonamides for obtaining isozyme-selective inhibitors?

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1. Sulfonamide carbonic anhydrase inhibitors: Zinc coordination and tail effects influence inhibitory efficacy and selectivity for different isoforms;Inorganica Chimica Acta;2018-01

2. Thermodynamic, kinetic, and structural parameterization of human carbonic anhydrase interactions toward enhanced inhibitor design;Quarterly Reviews of Biophysics;2018

3. Spectroscopy (FT-IR, FT-Raman), hydrogen bonding, electrostatic potential and HOMO-LUMO analysis of tioxolone based on DFT calculations;Journal of Molecular Structure;2016-10

4. Structural and Kinetic Effects on Changes in the CO2 Binding Pocket of Human Carbonic Anhydrase II;Biochemistry;2012-11-02

5. Carbonic anhydrase inhibitors and activators for novel therapeutic applications;Future Medicinal Chemistry;2011-07

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