Discovery of the First Potent, Selective 5-Hydroxytryptamine1D Receptor Antagonist
Author:
Affiliation:
1. Psychiatry Centre of Excellence for Drug Discovery, GlaxoSmithKline, New Frontiers Science Park, Third Avenue, Harlow, Essex, CM19 5AW, U.K.
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm049039v
Reference19 articles.
1. Alignment of receptor nomenclature with the human genome: classification of 5-HT1B and 5-HT1D receptor subtypes
2. Molecular, pharmacological and functional diversity of 5-HT receptors
3. A review of central 5-HT receptors and their function
4. A single amino-acid difference confers major pharmacological variation between human and rodent 5-HT1B receptors
5. Quantitative autoradiography of multiple 5-HT1 receptor subtypes in the brain of control or 5,7-dihydroxytryptamine-treated rats
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