General Approach for Preparing Epidithiodioxopiperazines from Trioxopiperazine Precursors: Enantioselective Total Syntheses of (+)- and (−)-Gliocladine C, (+)-Leptosin D, (+)-T988C, (+)-Bionectin A, and (+)-Gliocladin A-Reference-Cited by-同舟云学术

General Approach for Preparing Epidithiodioxopiperazines from Trioxopiperazine Precursors: Enantioselective Total Syntheses of (+)- and (−)-Gliocladine C, (+)-Leptosin D, (+)-T988C, (+)-Bionectin A, and (+)-Gliocladin A

Published:2013-03-01 Issue:10 Volume:135 Page:4117-4128
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

DeLorbe John E.¹,Horne David²,Jove Richard²,Mennen Steven M.¹,Nam Sangkil²,Zhang Fang-Li¹,Overman Larry E.¹

Affiliation:

1. Department of Chemistry, 1102 Natural Sciences II, University of California, Irvine, California 92697-2025, United States

2. Department of Molecular Medicine, Beckman Research Institute, City of Hope Comprehensive Cancer Center, 1500 East Duarte Road, Duarte, California 91010, United States

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja400315y

Reference62 articles.

1. Gliotoxin Is a Dual Inhibitor of Farnesyltransferase and Geranylgeranyltransferase I with Antitumor Activity Against Breast Cancer In Vivo

2. The chemistry and biology of the immunomodulating agent gliotoxin and related epipolythiodioxopiperazines

3. Epipolythiodioxopiperazines from Fungi: Chemistry and Bioactivities

4. 2,5-Diketopiperazines as Neuroprotective Agents

5. 2,5-Diketopiperazines: Synthesis, Reactions, Medicinal Chemistry, and Bioactive Natural Products

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