Discovery of a Tetrazole-Based Growth Hormone Secretagogue: 4-(Hydroxybutyl)carbamic Acid 2-{5-[1-(2-Amino-2-methylpropionylamino)-2- benzyloxyethyl]tetrazol-1-yl}ethyl Ester (BMS-317180)-Reference-Cited by-同舟云学术

Discovery of a Tetrazole-Based Growth Hormone Secretagogue: 4-(Hydroxybutyl)carbamic Acid 2-{5-[1-(2-Amino-2-methylpropionylamino)-2- benzyloxyethyl]tetrazol-1-yl}ethyl Ester (BMS-317180)

Published:2007-10-31 Issue:24 Volume:50 Page:5890-5893
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Li Jun¹,Chen Stephanie Y.¹,Li James J.¹,Wang Haixia¹,Hernandez Andres S.¹,Tao Shiwei¹,Musial Christa M.¹,Qu Fucheng¹,Swartz Stephen¹,Chao Sam T.¹,Flynn Neil¹,Murphy Brian J.¹,Slusarchyk Dorothy A.¹,Seethala Ramakrishna¹,Yan Mujing¹,Sleph Paul¹,Grover Gary¹,Smith Mark A.¹,Beehler Blake¹,Giupponi Leah¹,Dickinson Kenneth E.¹,Zhang Hongjian¹,Humphreys William G.¹,Patel Bharat P.¹,Schwinden Mark¹,Stouch Terry¹,Cheng Peter T. W.¹,Biller Scott A.¹,Ewing William R.¹,Gordon David¹,Robl Jeffrey A.¹,Tino Joseph A.¹

Affiliation:

1. Departments of Discovery Chemistry, Metabolic Diease, Metabolism and Pharmacokinetics, and Process Chemistry, Bristol-Myers Squibb Pharmaceutical Research Institute, Building 13, P.O. Box 5400, Princeton New Jersey 08543

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm7010595

Reference37 articles.

1. Design, Synthesis, and Biological Activity of Peptides which Release Growth Hormone in Vitro*

2. On thein Vitroandin VivoActivity of a New Synthetic Hexapeptide that Acts on the Pituitary to Specifically Release Growth Hormone*

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