Role of Induced Fit in Limiting Discrimination against AZT by HIV Reverse Transcriptase
Author:
Affiliation:
1. Department of Chemistry and Biochemistry, Institute for Cell and Molecular Biology, The University of Texas at Austin,2500 Speedway, MBB 3.122, Austin, Texas 78712, United States
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi200204m
Reference20 articles.
1. Mechanism and fidelity of HIV reverse transcriptase.
2. Structure and Function of HIV-1 Reverse Transcriptase: Molecular Mechanisms of Polymerization and Inhibition
3. Structural Determinants and Molecular Mechanisms for the Resistance of HIV-1 RT to Nucleoside Analogues
4. CONFORMATIONAL COUPLING IN DNA POLYMERASE FIDELITY
5. Reexamination of induced fit as a determinant of substrate specificity in enzymic reactions
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