Synthesis and in Vitro Activity of 3β-Substituted-3α-hydroxypregnan-20-ones: Allosteric Modulators of the GABAA Receptor-Reference-Cited by-同舟云学术

Synthesis and in Vitro Activity of 3β-Substituted-3α-hydroxypregnan-20-ones: Allosteric Modulators of the GABAA Receptor

Published:1997-01-01 Issue:1 Volume:40 Page:61-72
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hogenkamp Derk J.¹,Tahir S. Hasan¹,Hawkinson Jon E.¹,Upasani Ravi B.¹,Alauddin Mian¹,Kimbrough Catherine L.¹,Acosta-Burruel Manuel¹,Whittemore E. R.¹,Woodward R. M.¹,Lan Nancy C.¹,Gee Kelvin W.¹,Bolger Michael B.¹

Affiliation:

1. CoCensys, Inc., 213 Technology Drive, Irvine, California 92618, Department of Radiology, School of Medicine, and Department of Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, California 90033, and Department of Pharmacology, College of Medicine, University of California, Irvine, California 92717

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm960021x

Reference54 articles.

1. Steroids. CCCX. Structure-activity relation of some steroidal hypnotic agents

2. Anesthetic steroid mobility in model membrane preparations examined by high-resolution proton and deuterium NMR spectroscopy

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