Theoretical Study of Inhibition of Adenosine Deaminase by (8R)-Coformycin and (8R)-Deoxycoformycin-Reference-Cited by-同舟云学术

Theoretical Study of Inhibition of Adenosine Deaminase by (8R)-Coformycin and (8R)-Deoxycoformycin

Published:1996-01-01 Issue:1 Volume:39 Page:277-284
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Marrone Tami J.¹,Straatsma T. P.¹,Briggs James M.¹,Wilson David K.¹,Quiocho Florante A.¹,McCammon J. Andrew¹

Affiliation:

1. Departments of Chemistry and Biochemistry and of Pharmacology, University of California, San Diego, La Jolla, California 92093-0365, Pacific Northwest Laboratories, Battelle Boulevard, Richland, Washington 99352, and Department of Biochemistry and Howard Hughes Medical Institute, Baylor College of Medicine, Houston, Texas 77030

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9505674

Reference26 articles.

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2. Potential anti-AIDS drugs. Lipophilic, adenosine deaminase-activated prodrugs

3. Lipophilic, Acid-Stable, Adenosine Deaminase-Activated Anti-HIV Prodrugs for Central Nervous System Delivery. 2. 6-Halo- and 6-Alkoxy Prodrugs of 2'-.beta.-Fluoro-2',3'-dideoxyinosine

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