Formation of a Unique End-to-End Stacked Pair of G-Quadruplexes in the hTERT Core Promoter with Implications for Inhibition of Telomerase by G-Quadruplex-Interactive Ligands-Reference-Cited by-同舟云学术

Formation of a Unique End-to-End Stacked Pair of G-Quadruplexes in the hTERT Core Promoter with Implications for Inhibition of Telomerase by G-Quadruplex-Interactive Ligands

Published:2009-07-14 Issue:31 Volume:131 Page:10878-10891
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Palumbo SunMi L.¹,Ebbinghaus Scot W.¹,Hurley Laurence H.¹

Affiliation:

1. Arizona Cancer Center, University of Arizona, 1515 North Campbell Avenue, Tucson, Arizona 85724, College of Pharmacy, University of Arizona, Tucson, Arizona 85721, and BIO5 Institute, University of Arizona, 1657 East Helen Street, Tucson, Arizona 85721

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja902281d

Reference63 articles.

1. Telomerase activity in human germline and embryonic tissues and cells

2. Telomeres, telomerase and cancer: an up-date

3. Telomerase Expression in Noncancerous Bronchial Epithelia Is a Possible Marker of Early Development of Lung Cancer

4. Telomerase and telomere dynamics in ageing and cancer: current status and future directions

Cited by 232 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Modulation of dynamic DNA G-quadruplex structures in the hTERT promoter region by ligands;Nucleic Acids Research;2024-09-01

2. Discovery of telomerase inhibitors: existing strategies and emerging innovations;Biochemical Society Transactions;2024-08-28

3. Artificially inserted strong promoter containing multiple G-quadruplexes induces long-range chromatin modification;eLife;2024-08-19

4. Artificially inserted strong promoter containing multiple G-quadruplexes induces long-range chromatin modification;eLife;2024-08-19

5. Targeting hTERT Promoter G-Quadruplex DNA Structures with Small-Molecule Ligand to Downregulate hTERT Expression for Triple-Negative Breast Cancer Therapy;Journal of Medicinal Chemistry;2024-07-10