1. The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, People’s Republic of China, Shanghai Research Center for Modernization of TCM, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, People’s Republic of China, and Sino-US TCM Research Center and National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi, Mississippi 38677