(2R,1‘S,2‘R,3‘S)-2-(2‘-Carboxy-3‘-phenylcyclopropyl)glycine (PCCG-13), the First Potent and Selective Competitive Antagonist of Phospholipase D-Coupled Metabotropic Glutamate Receptors: Asymmetric Synthesis and Preliminary Biological Properties
Author:
Affiliation:
1. Istituto di Chimica e Tecnologia del Farmaco, Università di Perugia, Via del Liceo, 1-06123 Perugia, Italy, and Dipartimento di Farmacologia Preclinica e Clinica, Università di Firenze, Viale G. Pieraccini, 6-50139 Firenze, Italy
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm990128v
Reference19 articles.
1. Glutamate Activates Phospholipase D in Hippocampal Slices of Newborn and Adult Rats
2. Protein kinase C - a question of specificity
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