Novel CDC25A Phosphatase Inhibitors from Pyrolysis of 3-α-Azido-B-homo-6-oxa-4-cholesten-7-one on Silica Gel-Reference-Cited by-同舟云学术

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Novel CDC25A Phosphatase Inhibitors from Pyrolysis of 3-α-Azido-B-homo-6-oxa-4-cholesten-7-one on Silica Gel

Published:1998-10-31 Issue:24 Volume:41 Page:4677-4680
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Peng Hairuo¹,Zalkow Leon H.¹,Abraham Robert T.²,Powis Garth³

Affiliation:

1. School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332

2. Department of Immunology and Pharmacology, Mayo Clinic, Rochester, Minnesota 55905

3. Arizona Cancer Center, University of Arizona, 1515 North Campbell Avenue, Tucson, Arizona 85724-5024

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm980500r

Reference17 articles.

1. Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins

2. Cdc25A is a novel phosphatase functioning early in the cell cycle.

3. (b) Hoffmann, I.; Draetta, G.; Karsenti, E.; Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transitionEMBO J1994,13, 4302−4310.

4. CDC25 Phosphatases as Potential Human Oncogenes

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