Solution Structure of an Intramolecular (3 + 1) Human Telomeric G-Quadruplex Bound to a Telomestatin Derivative-Reference-Cited by-同舟云学术

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Solution Structure of an Intramolecular (3 + 1) Human Telomeric G-Quadruplex Bound to a Telomestatin Derivative

Published:2013-08-27 Issue:36 Volume:135 Page:13495-13501
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Chung Wan Jun¹,Heddi Brahim¹,Tera Masayuki²³,Iida Keisuke²,Nagasawa Kazuo²,Phan Anh Tuân¹

Affiliation:

1. School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore

2. Department of Biotechnology and Life Science, Faculty of Technology, Tokyo University of Agriculture and Technology, Japan

3. Bioorganic Research Institute, Suntory Foundation for Life Science, Japan

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja405843r

Reference72 articles.

1. A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes.

2. Normal human chromosomes have long G-rich telomeric overhangs at one end

3. Shelterin: the protein complex that shapes and safeguards human telomeres

4. Protection of mammalian telomeres

5. Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection

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