Chemical Decomposition of 5-Aza-2′-deoxycytidine (Decitabine): Kinetic Analyses and Identification of Products by NMR, HPLC, and Mass Spectrometry
Author:
Affiliation:
1. Department of Basic Sciences, Loma Linda University School of Medicine, Alumni Hall for Basic Science, Room 101, 11021 Campus Street, Loma Linda, California 92350
Publisher
American Chemical Society (ACS)
Subject
Toxicology,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/tx900131u
Reference39 articles.
1. Kinetics of phosphorylation of 5-aza-2′-deoxycytidine by deoxycytidine kinase
2. Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine.
3. 5-Azacytidine and 5-aza-2′-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy
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