Synthesis and Biological Evaluation of C-5 Methyl Substituted 4-Arylthio and 4-Aryloxy-3-Iodopyridin-2(1H)-one Type Anti-HIV Agents-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of C-5 Methyl Substituted 4-Arylthio and 4-Aryloxy-3-Iodopyridin-2(1H)-one Type Anti-HIV Agents

Published:2009-07-31 Issue:23 Volume:52 Page:7473-7487
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Guillemont Jérôme¹,Benjahad Abdellah²,Oumouch Said²,Decrane Laurence¹,Palandjian Patrice¹,Vernier Daniel¹,Queguiner Laurence¹,Andries Koen³,de Béthune Marie-Pierre⁴,Hertogs Kurt⁴,Grierson David S.²,Nguyen Chi Hung²

Affiliation:

1. TIBOTEC, Medicinal Chemistry Department, Campus de Maigremont BP315, 27430 Val de Reuil, France

2. UMR 176 CNRS-Institut Curie, Laboratoire de Pharmacochimie, Section de Recherche, Bâtiment 110, Centre Universitaire, 91405 Orsay, France

3. Johnson&Johnson Pharmaceutical Research and Development, Virology Drug Discovery, Tumhoutseweg 30, B-2340 Beerse, Belgium

4. TIBOTEC, Generaal De Wittelaan L 11 B3, B-2800 Mechelen, Belgium

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm900802y

Reference32 articles.

1. Highly Active Antiretroviral Therapy in a Large Urban Clinic: Risk Factors for Virologic Failure and Adverse Drug Reactions

2. Transmission of antiretroviral-drug-resistant HIV-1 variants

3. Diagnosis, prediction, and natural course of HIV-1 protease-inhibitor-associated lipodystrophy, hyperlipidaemia, and diabetes mellitus: acohort study

4. Adverse effects of antiretroviral therapy

5. Association between altered expression of adipogenic factor SREBP1 in lipoatrophic adipose tissue from HIV-1-infected patients and abnormal adipocyte differentiation and insulin resistance

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