Pyrazolo[3,4-d]pyrimidines as Potent Antiproliferative and Proapoptotic Agents toward A431 and 8701-BC Cells in Culture via Inhibition of c-Src Phosphorylation-Reference-Cited by-同舟云学术

Pyrazolo[3,4-d]pyrimidines as Potent Antiproliferative and Proapoptotic Agents toward A431 and 8701-BC Cells in Culture via Inhibition of c-Src Phosphorylation

Published:2006-02-09 Issue:5 Volume:49 Page:1549-1561
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Carraro Fabio¹,Naldini Antonella¹,Pucci Annalisa¹,Locatelli Giada A.¹,Maga Giovanni¹,Schenone Silvia¹,Bruno Olga¹,Ranise Angelo¹,Bondavalli Francesco¹,Brullo Chiara¹,Fossa Paola¹,Menozzi Giulia¹,Mosti Luisa¹,Modugno Michele¹,Tintori Cristina¹,Manetti Fabrizio¹,Botta Maurizio¹

Affiliation:

1. Dipartimento di Fisiologia, Sezione di Neuroimmunofisiologia, Università degli Studi di Siena, Via Aldo Moro, I-53100, Siena, Italy, Istituto di Genetica Molecolare, IGM-CNR, Via Abbiategrasso 207, I-27100, Pavia, Italy, Dipartimento di Scienze Farmaceutiche, Università degli Studi di Genova, Viale Benedetto XV, I-16132, Genova, Italy, and Dipartimento Farmaco Chimico Tecnologico, Università degli Studi di Siena, Via Alcide de Gasperi 2, I-53100, Siena, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm050603r

Reference48 articles.

1. Vertebrate non-receptor protein-tyrosine kinase families

2. Signal transduction by receptors with tyrosine kinase activity

3. Receptor Protein-Tyrosine Kinases and Their Signal Transduction Pathways

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