Selective Kainate Receptor (GluK1) Ligands Structurally Based upon 1H-Cyclopentapyrimidin-2,4(1H,3H)-dione: Synthesis, Molecular Modeling, and Pharmacological and Biostructural Characterization
Author:
Affiliation:
1. Dipartimento di Chimica Farmaceutica e Tossicologica, Università di Napoli Federico II, via D. Montesano 49, 80131 Napoli, Italy
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm2004078
Reference46 articles.
1. Glutamate as a Neurotransmitter in the Brain: Review of Physiology and Pathology
2. GluR7 is an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses
3. X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor
4. Kainate receptors and synaptic transmission
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