Selective Kainate Receptor (GluK1) Ligands Structurally Based upon 1H-Cyclopentapyrimidin-2,4(1H,3H)-dione: Synthesis, Molecular Modeling, and Pharmacological and Biostructural Characterization-Reference-Cited by-同舟云学术

Selective Kainate Receptor (GluK1) Ligands Structurally Based upon 1H-Cyclopentapyrimidin-2,4(1H,3H)-dione: Synthesis, Molecular Modeling, and Pharmacological and Biostructural Characterization

Published:2011-06-13 Issue:13 Volume:54 Page:4793-4805
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Venskutonytė Raminta,Butini Stefania,Sanna Coccone Salvatore,Gemma Sandra,Brindisi Margherita,Kumar Vinod,Guarino Egeria,Maramai Samuele,Valenti Salvatore,Amir Ahmad,Valadés Elena Antón,Frydenvang Karla,Kastrup Jette S.,Novellino Ettore¹,Campiani Giuseppe,Pickering Darryl S.

Affiliation:

1. Dipartimento di Chimica Farmaceutica e Tossicologica, Università di Napoli Federico II, via D. Montesano 49, 80131 Napoli, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm2004078

Reference46 articles.

1. Glutamate as a Neurotransmitter in the Brain: Review of Physiology and Pathology

2. GluR7 is an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses

3. X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

4. Kainate receptors and synaptic transmission

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