Targeted Drug Delivery to Chemoresistant Cells: Folic Acid Derivatization of FdUMP[10] Enhances Cytotoxicity toward 5-FU-Resistant Human Colorectal Tumor Cells-Reference-Cited by-同舟云学术

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Targeted Drug Delivery to Chemoresistant Cells: Folic Acid Derivatization of FdUMP[10] Enhances Cytotoxicity toward 5-FU-Resistant Human Colorectal Tumor Cells

Published:2001-08-01 Issue:17 Volume:66 Page:5655-5663
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Liu Jinqian¹,Kolar Carol¹,Lawson Terrence A.¹,Gmeiner William H.¹

Affiliation:

1. Eppley Institute, University of Nebraska Medical Center, Omaha, Nebraska 68198-6805

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo005757n

Reference42 articles.

1. Mechanisms of Acquired Resistance to Thymidylate Synthase Inhibitors: The Role of Enzyme Stability

2. Thymidylate synthase gene amplification in human colon cancer cell lines resistant to 5-fluorouracil

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