A New Approach to Rapid Parallel Development of Four Neurokinin Antagonists. Part 4. Synthesis of ZD2249 Methoxy Sulfoxide-Reference-Cited by-同舟云学术

A New Approach to Rapid Parallel Development of Four Neurokinin Antagonists. Part 4. Synthesis of ZD2249 Methoxy Sulfoxide

Published:2003-12-05 Issue:1 Volume:8 Page:33-44
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Bowden Sharon A.¹,Burke J. Nigel¹,Gray Fiona¹,McKown Steven¹,Moseley Jonathan D.¹,Moss William O.¹,Murray Paul M.¹,Welham Matthew J.¹,Young Maureen J.¹

Affiliation:

1. AstraZeneca, Process Research and Development, Avlon Works, Severn Road, Hallen, Bristol, BS10 7ZE, UK, and Large Scale Laboratory, Macclesfield, UK

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op030039z

Reference16 articles.

1. Discovery of novel, orally active dual NK1/NK2 antagonists

2. A New Approach to the Rapid Parallel Development of Four Neurokinin Antagonists. Part 3. Assembly of Neurokinin Antagonists

3. A New Approach to the Rapid Parallel Development of Four Neurokinin Antagonists. Part 5. Preparation of ZM374979 Cyanoacid and Selective Crystallisation of ZM374979 Atropisomers

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