1. Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Heyrovského 1203, CZ-500 05 Hradec Králové, Czech Republic, Department of Pathology and Bosch Institute, Faculty of Medicine, University of Sydney, Sydney, New South Wales 2006, Australia, Department of Clinical Microbiology, Charles University Medical School and Teaching Hospital, Sokolská 581, CZ-500 05 Hradec Králové, Czech Republic, and Zentiva, a. s., U Kabelovny 130, CZ-102 37, Prague, Czech Republic