Discovery of Novel Benzimidazoles as Potent Inhibitors of TIE-2 and VEGFR-2 Tyrosine Kinase Receptors-Reference-Cited by-同舟云学术

Discovery of Novel Benzimidazoles as Potent Inhibitors of TIE-2 and VEGFR-2 Tyrosine Kinase Receptors

Published:2007-08-04 Issue:18 Volume:50 Page:4453-4470
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hasegawa Masaichi¹,Nishigaki Naohiko¹,Washio Yoshiaki¹,Kano Kazuya¹,Harris Philip A.¹,Sato Hideyuki¹,Mori Ichiro¹,West Rob I.¹,Shibahara Megumi¹,Toyoda Hiroko¹,Wang Liping¹,Nolte Robert T.¹,Veal James M.¹,Cheung Mui¹

Affiliation:

1. Tsukuba Research Laboratories, GlaxoSmithKline K.K., 43 Wadai, Tsukuba, Ibaraki 300-4247, Japan, and GlaxoSmithKline Inc., Five Moore Drive, Research Triangle Park, North Carolina 27709

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0611051

Reference31 articles.

1. Vascular-targeting therapies for treatment of malignant disease

2. Targeting Vascular Endothelial Growth Factor Blockade: Ascites and Pleural Effusion Formation

3. Development of Vascular Endothelial Growth Factor Receptor (VEGFR) Kinase Inhibitors as Anti-Angiogenic Agents in Cancer Therapy

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