Developing Bivalent Ligands to Target CUG Triplet Repeats, the Causative Agent of Myotonic Dystrophy Type 1
Author:
Affiliation:
1. Center for Biophysics and Computational Biology, University of Illinois, Urbana, Illinois 61801, United States
2. Department of Chemistry, University of Illinois, Urbana, Illinois 61801, United States
Funder
National Institutes of Health
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm400794z
Reference70 articles.
1. Therapeutics development in myotonic dystrophy type 1
2. A Muscleblind Knockout Model for Myotonic Dystrophy
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4. Structural insights into CUG repeats containing the ‘stretched U–U wobble’: implications for myotonic dystrophy
5. Identification of MBNL1 and MBNL3 domains required for splicing activation and repression
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