The Importance of the Scaffold for de Novo Enzymes: A Case Study with Kemp Eliminase
Author:
Affiliation:
1. Chemical Sciences Division, Lawrence Berkeley National Laboratories, Berkeley, California 94720, United States
Funder
Basic Energy Sciences
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/jacs.6b12265
Reference46 articles.
1. Catalytic efficiency of designed catalytic proteins
2. Electrostatic Origin of the Catalytic Power of Enzymes and the Role of Preorganized Active Sites
3. Electrostatic Basis for Enzyme Catalysis
4. De Novo Computational Design of Retro-Aldol Enzymes
5. Kemp elimination catalysts by computational enzyme design
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