Rational Drug Design Approach for Overcoming Drug Resistance: Application to Pyrimethamine Resistance in Malaria-Reference-Cited by-同舟云学术

Rational Drug Design Approach for Overcoming Drug Resistance: Application to Pyrimethamine Resistance in Malaria

Published:1998-03-25 Issue:9 Volume:41 Page:1367-1370
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

McKie James H.¹,Douglas Kenneth T.¹,Chan Cecil¹,Roser Simon A.¹,Yates Robert¹,Read Martin¹,Hyde John E.¹,Dascombe Michael J.¹,Yuthavong Yongyuth¹,Sirawaraporn Worachart¹

Affiliation:

1. School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester M13 9PL, U.K., Department of Biomolecular Sciences, UMIST, Manchester M60 1QD, U.K., School of Biological Sciences, University of Manchester, Manchester M13 9PT, U.K., National Science and Technology Development Agency, Rama VI Road, Bangkok 10400, Thailand, and Department of Biochemistry, Faculty of Science, Mahidol University, Rama VI Road, Bangkok 10400, Thailand

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm970845u

Reference27 articles.

1. Intermittent Trimethoprim-Sulfamethoxazole Compared with Dapsone-Pyrimethamine for the Simultaneous Primary Prophylaxis of Pneumocystis Pneumonia and Toxoplasmosis in Patients Infected with HIV

2. The Activity of Atovaquone (566C80) in Murine Toxoplasmosis Is Markedly Augmented when Used in Combination with Pyrimethamine or Sulfadiazine

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