Design, Synthesis, and Antibacterial Properties of Dual-Ligand Inhibitors of Acetyl-CoA Carboxylase-Reference-Cited by-同舟云学术

Design, Synthesis, and Antibacterial Properties of Dual-Ligand Inhibitors of Acetyl-CoA Carboxylase

Published:2014-10-15 Issue:21 Volume:57 Page:8947-8959
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Silvers Molly A.¹,Robertson Gregory T.²,Taylor Carol M.³,Waldrop Grover L.¹

Affiliation:

1. Division of Biochemistry and Molecular Biology, Louisiana State University, Baton Rouge, Louisiana 70803, United States

2. Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States

3. Department of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, United States

Funder

Division of Molecular and Cellular Biosciences

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm501082n

Reference44 articles.

1. CDC. Antibiotic Resistance Threats in the United States, 2013;U.S. Department of Health and Human Services, Centers for Disease Control and Prevention:Atlanta, GA, 2013; http://www.cdc.gov/drugresistance/threat-report-2013/.

2. Inhibiting Bacterial Fatty Acid Synthesis

3. Bacterial Fatty Acid Biosynthesis: Targets for Antibacterial Drug Discovery

4. Multi-subunit acetyl-CoA carboxylases

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