A Novel Local Recycling Mechanism That Enhances Enteric Bioavailability of Flavonoids and Prolongs Their Residence Time in the Gut-Reference-Cited by-同舟云学术

A Novel Local Recycling Mechanism That Enhances Enteric Bioavailability of Flavonoids and Prolongs Their Residence Time in the Gut

Published:2012-10-24 Issue:11 Volume:9 Page:3246-3258
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Xia Bijun¹,Zhou Qiong¹,Zheng Zhijie¹,Ye Ling¹,Hu Ming¹²,Liu Zhongqiu¹

Affiliation:

1. Department of Pharmaceutics, School of Pharmaceutical Sciences, Southern Medical University, 1838 N Guangzhou Avenue, Guangzhou, Guangdong 510515, China

2. Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, 1441 Moursund Street, Houston, Texas 77030, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp300315d

Reference37 articles.

1. Commentary: Bioavailability of Flavonoids and Polyphenols: Call to Arms

2. Metabolism of Flavonoids via Enteric Recycling: Role of Intestinal Disposition

3. Transport and metabolism of flavonoids from Chinese herbal remedy Xiaochaihu-tang across human intestinal Caco-2 cell monolayers1

4. Pharmacokinetics of baicalein, baicalin and wogonin after oral administration of a standardized extract ofScutellaria baicalensis, PF-2405 in rats

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