Potent and Prolonged Innate Immune Activation by Enzyme-Responsive Imidazoquinoline TLR7/8 Agonist Prodrug Vesicles-Reference-Cited by-同舟云学术

Potent and Prolonged Innate Immune Activation by Enzyme-Responsive Imidazoquinoline TLR7/8 Agonist Prodrug Vesicles

Published:2020-06-11 Issue:28 Volume:142 Page:12133-12139
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Wang Bi¹,Van Herck Simon²,Chen Yong²,Bai Xiangyang¹,Zhong Zifu³,Deswarte Kim⁴,Lambrecht Bart N.⁴⁵,Sanders Niek N.³^ORCID,Lienenklaus Stefan⁶,Scheeren Hans W.¹,David Sunil A.⁷^ORCID,Kiessling Fabian¹^ORCID,Lammers Twan¹⁸⁹^ORCID,De Geest Bruno G.²^ORCID,Shi Yang¹^ORCID

Affiliation:

1. Institute for Experimental Molecular Imaging, Uniklinik RWTH Aachen and Helmholtz Institute for Biomedical Engineering, Faculty of Medicine, RWTH Aachen University, 52074 Aachen, Germany

2. Department of Pharmaceutics, Ghent University, Ghent 9000, Belgium

3. Laboratory of Gene Therapy, Ghent University, Ghent 9820, Belgium

4. Department of Internal Medicine and Pediatrics, Ghent University, VIB Center for Inflammation Research, Ghent, Belgium

5. Department of Pulmonary Medicine, Erasmus University Medical Center, Rotterdam 3015, The Netherlands

6. Institute for Laboratory Animal Science and Institute of Immunology, Hannover Medical School, Hannover 30625, Germany

7. Virovax, Lawrence, Kansas 66047, United States

8. Department of Pharmaceutics, Utrecht University, 3584 CG Utrecht, The Netherlands

9. Department of Targeted Therapeutics, University of Twente, 7500 AE Enschede, The Netherlands

Funder

European Regional Development Fund

Deutsche Forschungsgemeinschaft

China Scholarship Council

H2020 European Research Council

Aachen Interdisciplinary Center for Clinical Research, RWTH Aachen University

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.0c01928

Reference43 articles.

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