How the Local Environment of Functional Sites Regulates Protein Function
Author:
Affiliation:
1. Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan
2. Department of Chemistry, National Tsing Hua University, Hsinchu 300, Taiwan
Funder
Academia Sinica
Ministry of Science and Technology, Taiwan
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/jacs.0c02430
Reference165 articles.
1. What is the total number of protein molecules per cell volume? A call to rethink some published values
2. Macromolecular crowding: an important but neglected aspect of the intracellular environment
3. Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder
4. The isomerase PIN1 controls numerous cancer-driving pathways and is a unique drug target
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