Synthesis and Biological Evaluation of Shishijimicin A-Type Linker-Drugs and Antibody

Synthesis and Biological Evaluation of Shishijimicin A-Type Linker-Drugs and Antibody–Drug Conjugates

Published:2020-07-14 Issue:29 Volume:142 Page:12890-12899
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Nicolaou K. C.¹,Li Ruofan¹,Chen Qifeng¹,Lu Zhaoyong¹,Pitsinos Emmanuel N.¹²^ORCID,Schammel Alexander³,Lin Baiwei³,Gu Christine³,Sarvaiya Hetal³,Tchelepi Robert³,Valdiosera Amanda³,Clubb Justin³^ORCID,Barbour Nicole³,Sisodiya Vikram³,Sandoval Joseph³,Lee Christina³,Aujay Monette³,Gavrilyuk Julia³

Affiliation:

1. Department of Chemistry, BioScience Research Collaborative, Rice University, 6100 Main Street, Houston, Texas 77005, United States

2. Laboratory of Natural Products Synthesis & Bioorganic Chemistry, Institute of Nanoscience and Nanotechnology, National Centre for Scientific Research “Demokritos”, 153 10 Agia Paraskevi, Greece

3. AbbVie, Inc., 400 East Jamie Court, South San Francisco, California 94080, United States

Funder

Welch Foundation

Cancer Prevention and Research Institute of Texas

AbbVie Stemcentrx, LLC.

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.0c06554

Reference29 articles.