Regioselective Synthesis of 2,8-Disubstituted 4-Aminopyrido[3,2-d]pyrimidine-6-carboxylic Acid Methyl Ester Compounds

Author:

Bouscary-Desforges Gwenaelle1,Bombrun Agnes1,Augustine John Kallikat2,Bernardinelli Gérald3,Quattropani Anna1

Affiliation:

1. Merck Serono S.A., 9, Chemin des Mines, 1202 Geneva, Switzerland

2. Syngene International Ltd., Biocon Park, Plot Nos. 2 & 3, Bommasandra-Jigani Road, Bangalore 560 099, India

3. Laboratoire de crystallographie, Université de Genève, 24, quai Ernest-Ansermet, 1211 Geneva, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Reference21 articles.

1. Synthesis and biological evaluation of 4-morpholino-2-phenylquinazolines and related derivatives as novel PI3 kinase p110α inhibitors

2. bRueckle, T.; Quattropani, A.; Pomel, V.; Dorbais, J.; Covini, D.; Bischoff, A.WO2006024666, 2006.

3. cParrish, C. A.; Newlander, K. A.WO2009039140, 2009.

4. dPomel, V.; Gaillard, P.; Desforges, G.; Quattropani, A.; Montagne, C.WO2010037765, 2010.

5. eMontagne, C.; Bombrun, A.; Desforges, G.; Quattropani, A.; Gaillard, P.WO2010091996, 2010.

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