1. ZyxBio, LLC, P.O. Box 2255, Hudson, Ohio 44236, ZyxBio, LLC, 11,000 Cedar Avenue, Cleveland, Ohio 4106, College of Pharmacy, University of Michigan, Ann Arbor, Michigan, Novartis Pharmaceuticals, East Hanover, New Jersey, Johnson & Johnson Pharmaceutical Research & Development, LLC, and Aventis Pharmaceuticals, Bridgewater, New Jersey